The Psychiatry Wiki

I · The Big Picture

1 Why We're Here 2 The Arc of Psychiatric Medicine 3 What It Takes to Make a Medicine 4 The Psychedelic Frontier 5 Why Trials Are Slow

II · The Language & Map

6 How Psychiatry Is Organized 7 Episodes vs. Traits · The Clusters 8 Dating the Episode 9 Generics, Brands & Classes

III · The Conditions

In DSM-5-TR chapter order. Dim entries are still being written.

Neurodevelopmental

10 ADHD 11 Autism spectrum

Schizophrenia spectrum & psychotic

12 Schizophrenia & psychosis

Bipolar & related

13 Bipolar & bipolar depression

Depressive

14 Major depressive disorder · Persistent depressive disordersoon · Premenstrual dysphoric disordersoon

Anxiety

15 Generalized anxiety disorder · Panic disordersoon · Social anxiety disordersoon

Obsessive-compulsive & related

· OCDsoon · Body dysmorphic disordersoon

Trauma- & stressor-related

16 PTSD · Adjustment disordersoon

Feeding & eating

· Anorexia nervosasoon · Bulimia nervosasoon · Binge-eating disordersoon · ARFIDsoon

Sleep-wake

· Insomnia disordersoon

Substance-related & addictive

· Alcohol use disordersoon · Opioid use disordersoon

Personality

· Borderline personality disordersoon

IV · Pharmacology

17 Half-Life, Steady State & Washout 18 PK Draws & the PK Curve

V · The Mechanism Lab

✦ How the Medicines Work

By drug class. Dim entries are still being written.

Mood & anxiety

19 Antidepressants 20 Mood stabilizers 21 Anxiolytics & sedatives (GABA) · Buspirone, hydroxyzine & the non-GABA anxiolyticssoon

Psychosis & cognition

22 Antipsychotics · Muscarinic & the new antipsychoticssoon · Cognitive enhancers & dementia medicinessoon

Attention, arousal & sleep

23 Stimulants & ADHD medicines · Sleep medicines: orexin & melatoninsoon

Psychedelic & rapid-acting

24 Psychedelics (5-HT2A) 25 MDMA & entactogens 26 Ketamine & dissociatives

Addiction medicines

· Opioids & opioid-use treatmentsoon · Alcohol & nicotine medicinessoon · Cannabinoidssoon

Hormones & metabolism

· Neurosteroids & reproductive hormonessoon · GLP-1s, appetite & the brainsoon ✦ The Bloom Board · every bloom

VI · Beyond the Molecule

27 Same Drug, Different Delivery 28 Routes & Bioavailability 29 Pharmacogenomics & CYP450

Appendix

A1 Cheat Sheets & Rating Scales A2 The Mnemonics A3 Master Glossary